Phytosterol intake and overall survival in newly diagnosed ovarian cancer patients: An ambispective cohort study.

ABSTRACT:

Background

Phytosterol is a bioactive compound existing in all plant foods, which might have anticancer properties. The aim of this study was to first assess the impact of the pre-diagnosis phytosterol intake on overall survival (OS) of patients with ovarian cancer (OC).

Materials and methods

This ambispective cohort study recruited 703 newly diagnosed OC patients to investigate the aforementioned associations. Dietary intake was assessed using a validated 111-item food frequency questionnaire. Deaths were ascertained until March 31, 2021, through active follow-up and medical records. Cox proportional hazards regression models were applied to calculate the hazard ratios (HRs) and 95% confidence intervals (CIs).

Results

During the median follow-up of 37.17 months, 130

SUBMITTER: Zhao JQ 

PROVIDER: S-EPMC9452643 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature