Development of a deprescribing manual for frail older people for use in the COFRAIL study and in primary care.

ABSTRACT:

Introduction

Many older adults are affected by multimorbidity and subsequent polypharmacy which is associated with adverse outcomes. This is especially relevant for frail older patients. Polypharmacy may be reduced via deprescribing. As part of the complex intervention in the COFRAIL study, we developed a deprescribing manual to be used by general practitioners (GPs) in family conferences, in which GPs, patients and caregivers jointly discuss treatments.

Methods

We selected indications with a high prevalence in older adults in primary care (e.g. diabetes mellitus, hypertension) and conducted a literature search to identify deprescribing criteria for these indications. We additionally reviewed clinical practice guidelines. Based on the extracted information, we created a depr

SUBMITTER: Mann NK 

PROVIDER: S-EPMC9452796 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature