Health-related quality of life in hemoglobinopathies: A systematic review from a global perspective.

ABSTRACT:

Background

Sickle cell disease (SCD) and thalassemia are inherited blood disorders, which can lead to life-threatening events and chronic organ damage. Recent advances in treatments have increased life expectancy, and hemoglobinopathies have become chronic illnesses with social and emotional impairments. Thus, health-related quality of life (HRQOL) assessment has a fundamental role in disease management and treatment, and generic and disease-specific questionnaires are reliable and validated measures to estimate disease burden. The heterogeneous distribution of treatment opportunities worldwide influences physical, social, and emotional disease perception.

Objectives

To review publications concerning HRQOL for SCD and thalassemia in different areas of the world in order to g

SUBMITTER: Rodigari F 

PROVIDER: S-EPMC9452907 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature