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Hypertension control in Kerala, India: A prescription-based study at primary and secondary level health care institutions.


ABSTRACT:

Objective

We undertook a prescription-based study to identify the provider and institution-level factors related to achieving guideline-recommended control of hypertension and diabetes mellitus in Kerala, India.

Methods

This cross-sectional study in primary and secondary care hospitals in Kerala included both public and private institutions. One practitioner was selected from each institution. Data on institutional and provider factors were collected using a structured questionnaire. Prescriptions were photographically captured and data on disease status and drugs prescribed were recorded. Factors associated with disease control were identified using binary logistic regression.

Results

Totally 4679 prescriptions were included for analysis. For hypertension-only patients, control levels were 31.5% and was significantly higher in public hospitals (Adjusted odds ratio (AOR) 1.96, 95% confidence intervals (CI) 1.50-2.57). Among patients with diabetes only, diabetes control was seen in 36.6%. When both conditions were present, control was achieved in only 17.0% patients. Being prescribed two or more drugs indicated lower control, whatever the respective condition. Among antihypertensive prescriptions rationality of 26.7% were questioned, such as lack of Renin Angiotensin System (RAS) inhibitor in diabetic hypertensives, dual RAS blockage, and indication for beta-blocker monotherapy.

Conclusions

In this prescription-based study in Kerala, India, a majority of hypertensive patients did not have controlled blood pressure levels, particularly if diabetes coexisted. This has serious implications as Kerala is the state with the highest burden of hypertension in India. Several prescription patterns were of questionable rationality. Further research and actions on rationality of anti-hypertensive prescriptions and barriers to treatment intensification is warranted.

SUBMITTER: Sreelal TP 

PROVIDER: S-EPMC9453055 | biostudies-literature | 2022 Jul-Aug

REPOSITORIES: biostudies-literature

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Hypertension control in Kerala, India: A prescription-based study at primary and secondary level health care institutions.

Sreelal Thekkumkara Prabhakaran TP   Thulaseedharan Jissa Vinoda JV   Nair Sanjeev S   Ravindran Rekha Melathuparambil RM   Vijayakumar Krishnapillai K   Varma Ravi Prasad RP  

Indian heart journal 20220527 4


<h4>Objective</h4>We undertook a prescription-based study to identify the provider and institution-level factors related to achieving guideline-recommended control of hypertension and diabetes mellitus in Kerala, India.<h4>Methods</h4>This cross-sectional study in primary and secondary care hospitals in Kerala included both public and private institutions. One practitioner was selected from each institution. Data on institutional and provider factors were collected using a structured questionnai  ...[more]

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