Anatomy and relationships of forelimb lymph nodes in Sprague-Dawley rats: A detailed dissecting approach.

ABSTRACT:

Background

Constructing a reliable animal model for preclinical treatment of secondary lymphedema is challenging because the anatomical characteristics near the lymph nodes are understudied. Therefore, this study examined the detailed anatomical relationship between the axillary lymph node flaps (ALNFs) and brachial lymph node flaps (BLNFs) in the forelimb of Sprague-Dawley (SD) rats.

Materials and methods

Ten male rats, weighing 250-300 g, were used. The ALNFs and BLNFs on either side of the rat forelimbs were dissected. The two lymph node flaps (LNFs) were immediately harvested to analyze their physical characteristics (via imaging process software) and microscopic structure (via histology examinations).

Results

A total of 20 ALNFs and BLNFs from 10 rats were harves

SUBMITTER: Chen L 

PROVIDER: S-EPMC9453151 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature