Close association between lifestyle and circulating FGF21 levels: A systematic review and meta-analysis.

ABSTRACT:

Background

The impact of lifestyle factors on circulating fibroblast growth factor 21 (cFGF21) remains unclear. We conducted this systematic review and meta-analysis to evaluate the association between lifestyle factors and cFGF21 levels.

Methods

We included studies that evaluated the effects of different lifestyles on cFGF21 concentration in adults, which included smoking, exercise, diets, alcohol consumption and weight loss. Random effects models or fixed effects models were used for meta-analysis to calculate the standardized mean difference (SMD) and 95% confidence interval according to the heterogeneity among studies. Study quality was assessed using the Newcastle-Ottawa Scale for cohort studies, the Joanna Briggs Institution Checklist for cross-sectional studies, and t

SUBMITTER: Qian Z 

PROVIDER: S-EPMC9453313 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature