Homeostatic response to sleep deprivation and circadian rhythmicity are intact in older adults with insomnia.

ABSTRACT:

Study objectives

We examined whether homeostatic sleep drive and circadian rhythmicity differ in older adults with insomnia (OAI) compared to older good sleepers (GS).

Methods

OAI (n = 37) and GS (n = 30) participated in a 60-h in-lab study with sleep deprivation and constant routine paradigms. Homeostatic sleep drive was assessed by examining the effect of sleep deprivation on delta EEG power and theta EEG power, and repeated sleep latency tests. Circadian rhythm was assessed with salivary melatonin (phase and amplitude), core body temperature (phase, amplitude, and mesor), and sleep latency during a constant routine paradigm. Mixed models were used to assess interactions of group (OAS vs GS) with homeostatic sleep and circadian effects.

Results

Compared to GS, OAI s

SUBMITTER: Tracy EL 

PROVIDER: S-EPMC9453614 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature