A statistical optimization by response surface methodology for the enhanced production of riboflavin from Lactobacillus plantarum-HDS27: A strain isolated from bovine milk.

ABSTRACT: In the present study, Lactobacillus plantarum-HDS27 strain isolated from bovine milk was used for the enhanced production of riboflavin. Production medium was optimized by one factor at a time with different parameters. Statistical optimization by Response surface methodology (RSM), central composite design was used to optimize variables such as pH, temperature, glucose, and yeast extract. The present study reveals the maximum riboflavin production by one factor at a time was obtained under the culture conditions; glucose, yeast extract, pH 6, the temperature at 40°C, and 3% of inoculum size. In RSM, analysis of variance for the responses was calculated. Among the tested variables, pH, yeast extract, and temperature showed significant impact on riboflavin production. Maximum amount

SUBMITTER: Hemalatha M 

PROVIDER: S-EPMC9453640 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature