Risk and Survival of Third Primary Cancers in a Population-Based Cohort of Breast Cancer Patients.

ABSTRACT:

Introduction

The growing number of women diagnosed with breast cancer (BCa) together with high survival has resulted in an increasing population of survivors at risk of subsequent primary cancers. This study aimed to estimate the long-term risk and survival of third primary cancers (TPCs) among females with a first primary BCa.

Methods

Breast first primary cancers (FPCs) from the Portuguese North Region Cancer Registry, diagnosed between 2000 and 2010 (n = 15,981), were followed for a TPC (December 31, 2015) and death from any cause (June 30, 2021). The cumulative incidence of and mortality among TPCs were estimated. To compare survival, female patients with a TPC were matched (1:1, by age group, years between FPC and second primary cancer [SPC] diagnosis, and SPC loc

SUBMITTER: Morais S 

PROVIDER: S-EPMC9453664 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature