Sex-specific patterns and lifetime risk of multimorbidity in the general population: a 23-year prospective cohort study.

ABSTRACT:

Background

Multimorbidity poses a major challenge for care coordination. However, data on what non-communicable diseases lead to multimorbidity, and whether the lifetime risk differs between men and women are lacking. We determined sex-specific differences in multimorbidity patterns and estimated sex-specific lifetime risk of multimorbidity in the general population.

Methods

We followed 6,094 participants from the Rotterdam Study aged 45 years and older for the occurrence of ten diseases (cancer, coronary heart disease, stroke, chronic obstructive pulmonary disease, depression, diabetes, dementia, asthma, heart failure, parkinsonism). We visualised participants' trajectories from a single disease to multimorbidity and the most frequent combinations of diseases. We calculated

SUBMITTER: Velek P 

PROVIDER: S-EPMC9454172 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature