Glutathione metabolism in Cryptocaryon irritans involved in defense against oxidative stress induced by zinc ions.

ABSTRACT:

Background

Cryptocaryon irritans is a fatal parasite for marine teleosts and causes severe economic loss for aquaculture. Galvanized materials have shown efficacy in controlling this parasite infestation through the release of zinc ions to induce oxidative stress.

Methods

In this study, the resistance mechanism in C. irritans against oxidative stress induced by zinc ions was investigated. Untargeted metabolomics analysis was used to determine metabolic regulation in C. irritans in response to zinc ion treatment by the immersion of protomonts in ZnSO₄ solution at a sublethal dose (20 μmol). Eight differential metabolites were selected to assess the efficacy of defense against zinc ion stimulation in protomonts of C. irritans. Furthermore, the mRNA relative levels o

SUBMITTER: Zhong ZH 

PROVIDER: S-EPMC9454189 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature