A more effective CT synthesizer using transformers for cone-beam CT-guided adaptive radiotherapy.

ABSTRACT:

Purpose

The challenge of cone-beam computed tomography (CBCT) is its low image quality, which limits its application for adaptive radiotherapy (ART). Despite recent substantial improvement in CBCT imaging using the deep learning method, the image quality still needs to be improved for effective ART application. Spurred by the advantages of transformers, which employs multi-head attention mechanisms to capture long-range contextual relations between image pixels, we proposed a novel transformer-based network (called TransCBCT) to generate synthetic CT (sCT) from CBCT. This study aimed to further improve the accuracy and efficiency of ART.

Materials and methods

In this study, 91 patients diagnosed with prostate cancer were enrolled. We constructed a transformer-based hierarchi

SUBMITTER: Chen X 

PROVIDER: S-EPMC9454309 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature