Ontology highlight
ABSTRACT:
SUBMITTER: Basilico B
PROVIDER: S-EPMC9454310 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
Basilico Bernadette B Palamà Ilaria Elena IE D'Amone Stefania S Lauro Clotilde C Rosito Maria M Grieco Maddalena M Ratano Patrizia P Cordella Federica F Sanchini Caterina C Di Angelantonio Silvia S Ragozzino Davide D Cascione Mariafrancesca M Gigli Giuseppe G Cortese Barbara B
Frontiers in oncology 20220825
The complexity of the microenvironment effects on cell response, show accumulating evidence that glioblastoma (GBM) migration and invasiveness are influenced by the mechanical rigidity of their surroundings. The epithelial-mesenchymal transition (EMT) is a well-recognized driving force of the invasive behavior of cancer. However, the primary mechanisms of EMT initiation and progression remain unclear. We have previously showed that certain substrate stiffness can selectively stimulate human GBM ...[more]