Pancreatic Cancer: Challenges and Opportunities in Locoregional Therapies.

ABSTRACT: Pancreatic cancer (PC) remains the seventh leading cause of cancer-related deaths worldwide and the third in the United States, making it one of the most lethal solid malignancies. Unfortunately, the symptoms of this disease are not very apparent despite an increasing incidence rate. Therefore, at the time of diagnosis, 45% of patients have already developed metastatic tumours. Due to the aggressive nature of the pancreatic tumours, local interventions are required in addition to first-line treatments. Locoregional interventions affect a specific area of the pancreas to minimize local tumour recurrence and reduce the side effects on surrounding healthy tissues. However, compared to the number of new studies on systemic therapy, very little research has been conducted on localised intervent

SUBMITTER: Bazeed AY 

PROVIDER: S-EPMC9454856 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature