Cost-Effectiveness of an Organized Lung Cancer Screening Program for Asbestos-Exposed Subjects.

ABSTRACT: Background: The National Lung Screening Trial (NLST) and NELSON study opened the debate on the relevance of lung cancer (LC) screening in subjects exposed to occupational respiratory carcinogens. This analysis reported the incremental cost-effectiveness ratios (ICER) of an organized LC screening program for an asbestos-exposed population. Methods: Using Markov modelization, individuals with asbestos exposure were either monitored without intervention or annual low-dose thoracic computed-tomography (LDTCT) scan LC screening. LC incidence came from a prospective observational cohort of subjects with occupational asbestos exposure. The intervention parameters were those of the NLST study. Utilities and LC-management costs came from published reports. A sensitivity analysis evalu

SUBMITTER: Gendarme S 

PROVIDER: S-EPMC9454930 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature