Musical Activity During Life Is Associated With Multi-Domain Cognitive and Brain Benefits in Older Adults.

ABSTRACT: Regular musical activity as a complex multimodal lifestyle activity is proposed to be protective against age-related cognitive decline and Alzheimer's disease. This cross-sectional study investigated the association and interplay between musical instrument playing during life, multi-domain cognitive abilities and brain morphology in older adults (OA) from the DZNE-Longitudinal Cognitive Impairment and Dementia Study (DELCODE) study. Participants reporting having played a musical instrument across three life periods (n = 70) were compared to controls without a history of musical instrument playing (n = 70), well-matched for reserve proxies of education, intelligence, socioeconomic status and physical activity. Participants with musical activity outperformed controls in global

SUBMITTER: Bottcher A 

PROVIDER: S-EPMC9454948 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature