Ontology highlight
ABSTRACT:
SUBMITTER: Dima D
PROVIDER: S-EPMC9454959 | biostudies-literature | 2022 Aug
REPOSITORIES: biostudies-literature
Dima Danai D Jiang Dongxu D Singh Divya Jyoti DJ Hasipek Metis M Shah Haikoo S HS Ullah Fauzia F Khouri Jack J Maciejewski Jaroslaw P JP Jha Babal K BK
Cancers 20220823 17
Multiple myeloma (MM) is a complex hematologic malignancy characterized by the uncontrolled proliferation of clonal plasma cells in the bone marrow that secrete large amounts of immunoglobulins and other non-functional proteins. Despite decades of progress and several landmark therapeutic advancements, MM remains incurable in most cases. Standard of care frontline therapies have limited durable efficacy, with the majority of patients eventually relapsing, either early or later. Induced drug resi ...[more]