Deep Insight of the Pathophysiology of Gestational Diabetes Mellitus.

ABSTRACT: Diabetes mellitus is a severe metabolic disorder, which consistently requires medical care and self-management to restrict complications, such as obesity, kidney damage and cardiovascular diseases. The subtype gestational diabetes mellitus (GDM) occurs during pregnancy, which severely affects both the mother and the growing foetus. Obesity, uncontrolled weight gain and advanced gestational age are the prominent risk factors for GDM, which lead to high rate of perinatal mortality and morbidity. In-depth understanding of the molecular mechanism involved in GDM will help researchers to design drugs for the optimal management of the condition without affecting the mother and foetus. This review article is focused on the molecular mechanism involved in the pathophysiology of GDM and the probabl

SUBMITTER: Sharma AK 

PROVIDER: S-EPMC9455072 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature