2021 update on thyroid-associated ophthalmopathy.

ABSTRACT:

Purpose

Our understanding of thyroid-associated ophthalmopathy (TAO, A.K.A Graves' orbitopathy, thyroid eye disease) has advanced substantially, since one of us (TJS) wrote the 2010 update on TAO, appearing in this journal.

Methods

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Results

Recent insights have resulted from important studies conducted by many different laboratory groups around the World. A clearer understanding of autoimmune diseases in general and TAO specifically emerged from the use of improved research methodologies. Several key concepts have matured over the past decade. Among them, those arising from the refinement of mouse models of TAO, early stage investigation into restoring immune tolerance in Graves' disease, and a hard-won acknowledgement that th

SUBMITTER: Neag EJ 

PROVIDER: S-EPMC9455782 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature