Cervicovaginal Microbiota Composition in <i>Chlamydia trachomatis</i> Infection: A Systematic Review and Meta-Analysis.

ABSTRACT: In healthy women, the cervicovaginal microbiota is characterized by the predominance of Lactobacillus spp., whereas the overgrowth of anaerobic bacteria leads to dysbiosis, known to increase the risk of acquiring genital infections like Chlamydia trachomatis. In the last decade, a growing body of research has investigated the composition of the cervicovaginal microbiota associated with chlamydial infection via 16s rDNA sequencing, with contrasting results. A systematic review and a meta-analysis, performed on the alpha-diversity indices, were conducted to summarize the scientific evidence on the cervicovaginal microbiota composition in C. trachomatis infection. Databases PubMed, Scopus and Web of Science were searched with the following strategy: "Chlamydia trachomatis

SUBMITTER: Di Pietro M 

PROVIDER: S-EPMC9455926 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature