Uneven Meibomian Gland Dropout in Patients with Meibomian Gland Dysfunction and Demodex Infestation.

ABSTRACT: The purpose of this study was to compare the differences between uneven meibomian gland (MG) atrophy with and without Demodex infestation based on the index of uneven atrophy score (UAS). In this retrospective cohort study, 158 subjects were recruited, including 66 subjects in the Demodex-positive MGD group, 49 subjects in the Demodex-negative MGD group, and 43 subjects as normal control. No significant difference was verified in OSDI, TMH, TBUT, CFS, lid margin score, and meibograde (all p > 0.05) between the Demodex-positive MGD group and the Demodex-negative MGD group. The UAS index of the upper eyelid or both eyelids was significantly higher in the Demodex-positive group in comparison with the normal control group and Demodex-negative group and the difference was statistically signific

SUBMITTER: Yu X 

PROVIDER: S-EPMC9457096 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature