Anticoagulation Strategies during Extracorporeal Membrane Oxygenation: A Narrative Review.

ABSTRACT: The development of extracorporeal life support technology has added a new dimension to the care of critically ill patients who fail conventional treatment options. Extracorporeal membrane oxygenation (ECMO)-specialized temporary life support for patients with severe cardiac or pulmonary failure-plays a role in bridging the time for organ recovery, transplant, or permanent assistance. The overall patient outcome is dependent on the underlying disease, comorbidities, patient reaction to critical illness, and potential adverse events during ECMO. Moreover, the contact of the blood with the large artificial surface of an extracorporeal system circuit triggers complex inflammatory and coagulation responses. These processes may further lead to endothelial injury and disrupted microcirculation wi

SUBMITTER: Rajsic S 

PROVIDER: S-EPMC9457503 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature