Ameliorative Effect of Pomegranate Peel Extract (PPE) on Hepatotoxicity Prompted by Iron Oxide Nanoparticles (Fe₂O₃-NPs) in Mice.

ABSTRACT: An evaluation of the ameliorative effect of pomegranate peel extract (PPE) in counteracting the toxicity of iron oxide nanoparticles (Fe₂O₃-NPs) that cause hepatic tissue damage is focused on herein. Forty male albino mice were haphazardly grouped into four groups as follows: the first control group was orally gavage daily with physiological saline; the second group received 100 mg/kg of PPE by the oral route day after day; the third group received 30 mg/kg Fe₂O₃-NPs orally; and the fourth group received both PPE and Fe₂O₃-NPs by the oral route, the same as the second and third sets. Later, after the completion of the experiment, we collected the liver, blood, and bone marrow of bone specimens that were obtained for further

SUBMITTER: Abd El-Aziz YM 

PROVIDER: S-EPMC9457799 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature