Does concomitant ductal carcinoma in situ affect the clinical outcome in breast cancer patients with invasive ductal carcinoma: An Asian perspective.

ABSTRACT:

Background

Ductal carcinoma in situ (DCIS) is an established precursor to invasive ductal carcinoma (IDC) and its coexistence with IDC appear to favor reduced biological aggressiveness. Its prognostic implication and ability to affect clinical outcome has been understudied in Asia. This study aims to explore if concomitant DCIS affects the clinical behavior and outcomes among Asians.

Aim

Stages I to III breast cancer patients with histological proven IDC, diagnosed and treated in a single institution from June 1, 2004 to June 30, 2014 were included in this study. Statistical analyses were conducted using Χ² test, independent t test, multivariate logistic regression and Kaplan-Meier test.

Methods and results

A total of 818 patients were identified, including

SUBMITTER: Lee WP 

PROVIDER: S-EPMC9458486 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature