Circular RNA MYLK as a prognostic biomarker in patients with cancers: A systematic review and meta-analysis.

ABSTRACT:

Background

Circular RNA (circRNA) myosin light chain kinase (circMYLK) has recently received increasing attention in cancer biology. Several studies have suggested that circMYLK expression is linked to prognosis and clinicopathological characteristics of various malignancies.

Aims

This study was carried out to systematically review the impact of circMYLK on the progression of multiple cancers and assess the significance of circMYLK in the prognosis and clinicopathological features of the patients.

Methods

PubMed, Web of Science, and Embase were systematically searched until July 2, 2021. For qualitative synthesis, the signaling pathways of circMYLK in the progression of different cancers were summarized. Regarding the meta-analysis, overall survival (OS) and eight cli

SUBMITTER: Foroumadi R 

PROVIDER: S-EPMC9458501 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature