A predictive model based on ground glass nodule features via high-resolution CT for identifying invasiveness of lung adenocarcinoma.

ABSTRACT:

Objective

The morphology of ground-glass nodule (GGN) under high-resolution computed tomography (HRCT) has been suggested to indicate different histological subtypes of lung adenocarcinoma (LUAD); however, existing studies only include the limited number of GGN characteristics, which lacks a systematic model for predicting invasive LUAD. This study aimed to construct a predictive model based on GGN features under HRCT for LUAD.

Methods

A total of 301 surgical LUAD patients with HRCT-confirmed GGN were enrolled, and their GGN-related features were assessed by 2 individual radiologists. The pathological diagnosis of the invasive LUAD was established by pathologic examination following surgery (including 171 invasive and 130 non-invasive LUAD patients).

Results

GGN featu

SUBMITTER: Yan B 

PROVIDER: S-EPMC9458920 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature