A Systematic Review of Reported Outcomes in ADPKD Studies.

ABSTRACT:

Introduction

Autosomal dominant polycystic kidney disease (ADPKD) is a progressive genetic kidney disease. Studies of ADPKD presented results using different outcome measures. We aimed to summarize outcomes reported in ADPKD studies, including composite outcomes.

Methods

We conducted a systematic review of published studies that included patients with ADPKD and measured kidney-related outcomes. We searched published databases and included all studies regardless of design with at least 100 participants for observational studies. We excluded studies that were limited to dialysis, transplant, or pregnancy outcomes in patients with ADPKD.

Results

This review includes data from 175 published articles (49 randomized controlled trials, 2 interventional clinical trials, 30

SUBMITTER: Jdiaa SS 

PROVIDER: S-EPMC9459055 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature