Rotavirus vaccination and the risk of type 1 diabetes and celiac disease: A systematic review and meta-analysis.

ABSTRACT:

Background

Rotavirus vaccination has been proven to effectively protect against rotavirus gastroenteritis. However, there are concerns about the relationship between rotavirus vaccination and the risk of autoimmune disorders. Thus, we conducted a systematic review and meta-analysis to comprehensively assess the association between rotavirus vaccination and type 1 diabetes (T1D) or celiac disease (CD) risk.

Methods

A systematic review and meta-analysis were conducted to evaluate the type 1 diabetes or celiac disease associated with rotavirus vaccination. The following journal databases were searched to identify potential studies for inclusion: PubMed, Embase, and Cochrane Library databases.

Results

Seven articles involving more than 5,793,055 children were included. Ou

SUBMITTER: Zhang X 

PROVIDER: S-EPMC9459138 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature