The role of Th9 CD4⁺ T cells and IL-9 during primary Sjogren's syndrome.

ABSTRACT:

Objective

The objective of this study is to investigate the expression levels of Th₉ CD4⁺ T cells and IL-9 secretion in peripheral blood mononuclear cells of patients with primary Sjogren's syndrome. Further, this study aimed to investigate the role of Th₉ cells in the occurrence and development of pSS.

Methods

A total of 20 pSS patients and 20 healthy people, matched with age and gender, were selected as the experimental and control group, respectively. Flow cytometry and ELISA were used to detect the expression of Th₉ cytokines in peripheral blood mononuclear cells and IL-9 in serum, respectively. These factors were then correlated to other clinical indicators.

Results

The levels of Th₉ CD4⁺ T cells a

SUBMITTER: Yang J 

PROVIDER: S-EPMC9459269 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature