Different functional lung-sparing strategies and radiotherapy techniques for patients with esophageal cancer.

ABSTRACT:

Background

Integration of 4D-CT ventilation function images into esophageal cancer radiation treatment planning aimed to assess dosimetric differences between different functional lung (FL) protection strategies and radiotherapy techniques.

Methods

A total of 15 patients with esophageal cancer who had 4D-CT scans were included. Lung ventilation function images based on Jacobian values were obtained by deformation image registration and ventilation imaging algorithm. Several different plans were designed for each patient: clinical treatment planning (non-sparing planning), the same beam distribution to FL-sparing planning, three fixed-beams FL-sparing intensity-modulated radiation therapy (IMRT) planning (5F-IMRT, 7F-IMRT, 9F-IMRT), and two FL-sparing volumetric modulated arc

SUBMITTER: Zhou PX 

PROVIDER: S-EPMC9459335 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature