Immune responses in COVID-19 and tuberculosis coinfection: A scoping review.

ABSTRACT:

Background and aim

Patients with COVID-19 and tuberculosis coinfection are at an increased risk of severe disease and death. We therefore sought to evaluate the current evidence which assessed the immune response in COVID-19 and tuberculosis coinfection.

Methods

We searched Pubmed/MEDLINE, EMBASE, Scopus, and Web of Science to identify articles published between 2020 and 2021. We included observational studies evaluating the immune response in patients with tuberculosis and COVID-19 compared to patients with COVID-19 alone.

Results

Four cross-sectional studies (372 participants) were identified. In patients with asymptomatic COVID-19 and latent tuberculosis (LTBI), increased cytokines, chemokines, growth factors and humoral responses were found. In addition, patients

SUBMITTER: Flores-Lovon K 

PROVIDER: S-EPMC9459402 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature