Intestinal Barrier Permeability in Obese Individuals with or without Metabolic Syndrome: A Systematic Review.

ABSTRACT: Altered intestinal barrier permeability has been associated with obesity and its metabolic and inflammatory complications in animal models. The purpose of this systematic review is to assess the evidence regarding the association between obesity with or without Metabolic Syndrome (MetS) and alteration of the intestinal barrier permeability in humans. A systematic search of the studies published up until April 2022 in Latin America & Caribbean Health Sciences Literature (LILACS), PubMed, Scopus, Embase, and ScienceDirect databases was conducted. The methodological quality of the studies was assessed using the Newcastle-Ottawa scale (NOS) and the Agency for Healthcare Research and Quality (AHRQ) checklist. The Grading of Recommendations Assessment, Development and Evaluation (GRADE) framewor

SUBMITTER: Bona MD 

PROVIDER: S-EPMC9459697 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature