State-of-the-Art and Opportunities for Bioactive Pentacyclic Triterpenes from Native Mexican Plants.

ABSTRACT: Native Mexican plants are a wide source of bioactive compounds such as pentacyclic triterpenes. Pentacyclic triterpenes biosynthesized through the mevalonate (MVA) and the 2-C-methyl-D-erythritol-phosphate (MEP) metabolic pathways are highlighted by their diverse biological activity. Compounds belonging to the oleanane, ursane, and lupane groups have been identified in about 33 Mexican plants, located geographically in the southwest of Mexico. The works addressing these findings have reported 45 compounds that mainly show antimicrobial activity, followed by anti-inflammatory, cytotoxic, anxiolytic, hypoglycemic, and growth-stimulating or allelopathic activities. Extraction by maceration and Soxhlet with organic solvents and consecutive chromatography of silica gel have been used for their

SUBMITTER: Alfaro-Almaguer JA 

PROVIDER: S-EPMC9459852 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature