YTH Domain Proteins Play an Essential Role in Rice Growth and Stress Response.

ABSTRACT: As the most prevalent epi-transcriptional modification, m⁶A modifications play essential roles in regulating RNA fate. The molecular functions of YTH521-B homology (YTH) domain proteins, the most known READER proteins of m⁶A modifications, have been well-studied in animals. Although plants contain more YTH domain proteins than other eukaryotes, little is known about their biological importance. In dicot species Arabidopsis thaliana, the YTHDFA clade members ECT2/3/4 and CPSF30-L are well-studied and important for cell proliferation, plant organogenesis, and nitrate transport. More emphasis is needed on the biological functions of plant YTH proteins, especially monocot YTHs. Here we presented a detailed phylogenetic relationship of eukaryotic YTH proteins and clustered

SUBMITTER: Ma W 

PROVIDER: S-EPMC9460353 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature