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Nanoparticle-Containing Hyaluronate Solution for Improved Lubrication of Orthopedic Ceramics.


ABSTRACT: Premature failure caused by inadequate lubrication of an artificial joint is a major problem. Inspired by engine lubrication, in which various additives are used to enforce the oil lubricant, here, a bench test of a biomimetic lubricating fluid containing different substances was carried out. Bovine serum albumin (BSA), in the form of both molecules and nanoparticles, was used as a functional additive. Compared with BSA molecules, BSA nanoparticles dispersed in HA solution served as more effective additives in the biomimetic lubrication fluid to minimize the friction and wear of ceramic orthopedic materials made of zirconium dioxide (ZrO2). Meanwhile, a tribo-acoustic study indicated that the "squeaking" problem associated with ZrO2 could be suppressed by the biomimet

SUBMITTER: Li W 

PROVIDER: S-EPMC9460720 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature