Amplitude of low-frequency fluctuation after a single-trigger pain in patients with classical trigeminal neuralgia.

ABSTRACT:

Objective

This study aimed to explore the central mechanism of classical trigeminal neuralgia (CTN) by analyzing the static amplitude of low-frequency fluctuation (sALFF) and dynamic amplitude of low-frequency fluctuation (dALFF) in patients with CTN before and after a single-trigger pain.

Methods

This study included 48 patients (37 women and 11 men, age 55.65 ± 11.41 years) with CTN. All participants underwent 3D-T1WI and three times resting-state functional magnetic resonance imaging. The images were taken before stimulating the trigger zone (baseline), within 5 s after stimulating the trigger zone (triggering-5 s), and in the 30th minute after stimulating the trigger zone (triggering-30 min). The differences between the three measurements were analyzed using a repeated-me

SUBMITTER: Ge X 

PROVIDER: S-EPMC9461270 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature