LiverMultiScan as an alternative to liver biopsy to monitor autoimmune hepatitis in the National Health Service in England: an economic evaluation.

ABSTRACT:

Background

Autoimmune hepatitis (AIH) is a rare chronic progressive liver disease, managed with corticosteroids and immunosuppressants and monitored using a combination of liver biochemistry and histology. Liver biopsy (gold standard) is invasive, costly and has risk of complications. Non-invasive imaging using multiparametric magnetic resonance (mpMR) can detect the presence and extent of hepatic fibroinflammation in a risk-free manner.

Objective

To conduct early economic modelling to assess the affordability of using mpMR as an alternative to liver biopsy.

Methods

Medical test costs associated with following 100 patients over a 5-year time horizon were assessed from a National Health Service payor perspective using tariff costs and average biopsy-related adverse eve

SUBMITTER: Bajre M 

PROVIDER: S-EPMC9462097 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature