(E)-3-{4,6-Dimeth­oxy-2-[(E)-4-meth­oxy­styr­yl]-3-methyl­phen­yl}-1-(2-hy­droxy-5-meth­oxy­phen­yl)prop-2-en-1-one

ABSTRACT: The crystal structure of a pharmacophore hybrid of chalcone and resveratrol is reported. In the title compound, C28H28O6, the benzene rings in the resveratrol moiety are connected by a trans C=C double bond, and the hydroxyl group containing a benzene ring and the central benzene ring are linked through a C=(O)—C=C (enone) moiety to form a chalcone unit. An intra­molecular O—H⋯O hydrogen bond generates an S(6) ring motif. In the crystal, pairs of C—H⋯O hydrogen bonds generate dimers and additional weak C—H⋯O inter­actions link the dimers into chains propagating along the b-axis direction.

SUBMITTER: Yoo M 

PROVIDER: S-EPMC9462233 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature