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(2R,4S,5S)-5-Meth-oxy-4-methyl-3-oxohept-6-en-2-yl benzoate.

ABSTRACT: The title compound, C₁₆H₂₀O₄, was synthesized in the course of the total synthesis of fusaequisin A in order to verify and confirm the configurations of the stereogenic centers and to exclude the possibility of epimerization during the methyl-ation process. The crystal structure of the title compound at 100 K has ortho-rhom-bic (P2₁2₁2₁) symmetry. The absolute configuration was determined by anomalous dispersion and agrees with the configuration of the allylic alcohol used in the synthesis.

SUBMITTER: Schmidt AC

PROVIDER: S-EPMC9462372 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature

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(2R,4S,5S)-5-Meth-oxy-4-methyl-3-oxohept-6-en-2-yl benzoate.

Schmidt Ann-Christin AC Iovkova Lyuba L Hiersemann Martin M

IUCrData 20210917 Pt 9

The title compound, C16H20O4, was synthesized in the course of the total synthesis of fusaequisin A in order to verify and confirm the configurations of the stereogenic centers and to exclude the possibility of epimerization during the methyl-ation process. The crystal structure of the title compound at 100 K has ortho-rhom-bic (P212121) symmetry. The absolute configuration was determined by anomalous dispersion and agrees ...[more]

PMID: 36338945

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