Case report: Acute vestibular syndrome and cerebellitis in anti-Yo paraneoplastic syndrome.

ABSTRACT:

Background

We define acute vestibular syndrome (AVS) as a sudden onset vertigo, nausea, vomiting, and head motion intolerance, more frequently associated with an acute peripheral and unilateral vestibulopathy. About 10-20% of all cases with central vestibulopathy are secondary to stroke. We report three patients evaluated over the past decade with an acute AVS along with subtle downbeat nystagmus (DBN), followed by dysarthria and progressive truncal and limb ataxia, as well as increasing DBN intensity.

Methods

All patients underwent neurologic examination, video-oculography, MRI, serum cancer markers, spinal fluid examination, paraneoplastic panel testing, and oncologic workup. With a consolidated diagnosis of cancer/paraneoplastic syndrome, we treated with plasma exchange (

SUBMITTER: Kherallah B 

PROVIDER: S-EPMC9462393 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature