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From Bowen disease to cutaneous squamous cell carcinoma: eight markers were verified from transcriptomic and proteomic analyses.


ABSTRACT:

SUBMITTER: Biao T 

PROVIDER: S-EPMC9462620 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature

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From Bowen disease to cutaneous squamous cell carcinoma: eight markers were verified from transcriptomic and proteomic analyses.

Biao Tang T   Cai-Feng He H   Xiao-Hong Lu L   Xiao-Li Chang C   Wen-Bei Liu L   Jun Wang W   Chao Ci C   Tao Yuan Y  

Journal of translational medicine 20220909 1


<h4>Background</h4>Bowen's disease is a cutaneous squamous cell carcinoma (CSCC) in situ. If left untreated, BD may progress to invasive CSCC. CSCC is one of the most common cutaneous carcinoma in the elderly and the advanced, metastasis CSCC usually have a poor outcomes. However, the mechanisms of invasion and metastasis from Bowen's disease to CSCC is complicated and still unclear.<h4>Objectives</h4>The aim of this study was to explore the biomarkers and molecular alterations in Bowen's diseas  ...[more]

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