Procalcitonin as a predictive marker in COVID-19: A systematic review and meta-analysis.

ABSTRACT:

Background

Coronavirus disease 2019 has emerged as a global pandemic causing millions of critical cases and deaths. Early identification of at-risk patients is crucial for planning triage and treatment strategies.

Methods and findings

We performed this systematic review and meta-analysis to determine the pooled prognostic significance of procalcitonin in predicting mortality and severity in patients with COVID-19 using a robust methodology and clear clinical implications.

Design

We used Preferred Reporting Items for Systematic Reviews and Meta-Analyses and Cochrane Handbook for Systematic Reviews of Interventions guidelines. We included thirty-two prospective and retrospective cohort studies involving 13,154 patients.

Results

The diagnostic odds ratio of procal

SUBMITTER: Kumar A 

PROVIDER: S-EPMC9462680 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature