Use of magnetic resonance elastography to gauge meningioma intratumoral consistency and histotype.

ABSTRACT:

Objective

To determine whether tumor shear stiffness, as measured by magnetic resonance elastography, corresponds with intratumoral consistency and histotype.

Materials and methods

A total of 88 patients with 89 meningiomas (grade 1, 74 typical [13 fibroblastic, 61 non-fibroblastic]; grade 2, 12 atypical; grade 3, 3 anaplastic) were prospectively studied, each undergoing preoperative MRE in conjunction with T1-, T2- and diffusion-weighted imaging. Contrast-enhanced T1-weighted sequences were also obtained. Tumor consistency was evaluated as heterogeneous or homogenous, and graded on a 5-point scale intraoperatively. MRE-determined shear stiffness was associated with tumor consistency by surgeon's evaluation and whole-slide histologic analyses.

Results

Mean tumor stiff

SUBMITTER: Shi Y 

PROVIDER: S-EPMC9463601 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature