Pulsed-field ablation: Computational modeling of electric fields for lesion depth analysis.

ABSTRACT:

Background

Pulsed-field ablation (PFA) is an emerging and promising nonthermal technology for cardiac ablation. The effective applied voltage to achieve adequate irreversible myocardial injury is not well studied. The pulsed-field strength remains independent of tissue contact; therefore, PFA is assumed to be an ablation technology, not mandating the need for tissue contact.

Objective

Determine the effect of applied voltage and distance to surface on depth of myocardial injury using PFA.

Methods

A computational model was developed and validated based on extracted data from in vivo studies to examine the effect of different applied voltages and the impact of distance between the catheter and endocardial surface on the depth of irreversible myocardial injury using PFA.<

SUBMITTER: Meckes D 

PROVIDER: S-EPMC9463712 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature