Impact of hemodynamic instability during cytoreductive surgery on survival in high-grade serous ovarian carcinoma.

ABSTRACT:

Background

To evaluate the impact of intraoperative hypotension and hemodynamic instability on survival outcomes in patients with high-grade serous ovarian carcinoma (HGSOC).

Methods

We retrospectively identified patients with HGSOC, who underwent primary or interval debulking surgery between August 2013 and December 2019. We collected anesthesia-related variables, including the arterial blood pressure measurements (at 1-min intervals) during the surgery of patients. The cumulative duration of mean arterial blood pressure (MAP) readings under 65 mmHg and two performance measurements (median performance error [MDPE] and wobble) were calculated. We investigated associations between the factors indicating hemodynamic instability and prognosis.

Results

In total, 338 patie

SUBMITTER: Kim SI 

PROVIDER: S-EPMC9463790 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature