Perfluoroalkyl substances (PFASs) as risk factors for breast cancer: a case-control study in Chinese population.

ABSTRACT:

Background

Perfluoroalkyl substances (PFASs) are a large family of synthetic chemicals, some of which are mammary toxicants and endocrine disruptors. Recent studies have implicated exposure to PFASs as a risk factor for breast cancer in Europe and America. Little is known about the role of PFASs with respect to breast cancer in the Chinese population.

Methods

Participants who were initially diagnosed with breast cancer at Tianjin Medical University Cancer Institute and Hospital between 2012 and 2016 were recruited as cases. The controls were randomly selected from the participants with available blood samples in the Chinese National Breast Cancer Screening Program (CNBCSP) cohort. Ultimately, we enrolled 373 breast cancer patients and 657 controls. Plasma PFASs were measured

SUBMITTER: Li X 

PROVIDER: S-EPMC9463854 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature