The effect of ageing on fat infiltration of thigh and paraspinal muscles in men.

ABSTRACT:

Background

Myosteatosis, skeletal muscle fat infiltration, is associated with inflammation and fibrosis. The age-related increase of myosteatosis is an important characteristic of sarcopenia and contributes to fragility.

Aims

To investigate the impact of healthy aging on intermuscular adipose tissue (IMAT) and muscle fat fraction (FF) in the thigh and the paraspinal muscles in males.

Methods

In 54 healthy males (age 20-70), all active hobby golfers, magnetic resonance imaging was performed to determine volume of IMAT, volume of muscle tissue (MT) and of percentage of FF.

Results

Between ages 20-70, at the thigh, IMAT/MT volume and MT FF increased annually by 2.9% and 1.3%, respectively. At the psoas IMAT/Psoas volume did not change with age. MT FF increased by

SUBMITTER: Engelke K 

PROVIDER: S-EPMC9464152 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature