Dataset Information

Natural Course of Muscular Strength, Physical Performance, and Musculoskeletal Symptoms in Hospitalized Patients with COVID-19.

ABSTRACT:

Objective

To investigate the course of muscle strength, musculoskeletal symptoms and physical performance over time in hospitalized COVID-19 patients, and their relationship with disease severity at admission.

Design

Prospective cohort study.

Setting

Pandemic clinic of Gazi University Hospital, Ankara, Turkey.

Participants

76 adult COVID-19 patients (age >18 years) were enrolled in the study between March 2021 and May 2021. The participants were grouped as "mild", "moderate", and "severe" according to clinical and radiological findings.

Outcome measures

The fraction of inspired oxygen (FiO2), oxygen saturation (SpO2), hand grip strength (HGS), 5-times sit and stand test (5XSTS), modified Borg scale at rest (mBorg-rest), modified Borg scale during activities of daily living (mBorg-ADL), Barthel index, and visual analog scale for myalgia (myalgia-VAS) values were recorded on the first day of hospitalization and in the first, third, and twelfth weeks. Outcome measures were compared between disease severity groups. In addition, the changes in these outcome measures over time were also examined.

Results

There were 15 (19,7%) participants in the mild, 20 (26,3%) in the moderate, and 41 (53,9%) in the severe groups. At the baseline evaluation, SpO2 (p<0.001), FiO2 (p<0.001), 5XSTS (p=0.002), mBorg-rest (p=0.016), and mBorg-ADL (p<0.001) were different in three groups but there were no differences for HGS, Barthel index, myalgia VAS score. HGS, 5XSTS, myalgia-VAS and mBorg-ADL scores improved significantly over time in all groups (p<0.001, p≤0.001, p<0.001 respectively). At the end of 12 weeks, only 5XSTS was different between the groups. 5XSTS was significantly longer in the severe group (p=0.010).

Conclusion

Although significant improvement was observed in the muscle strength, physical performance and musculoskeletal symptoms of patients with COVID-19 over time, the physical performance of these patients did not reach normal standards. We conclude that post-COVID-19 rehabilitation programs are needed to optimize the physical performance of the patients.

SUBMITTER: Karasu AU

PROVIDER: S-EPMC9464470 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature

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Publications

Natural Course of Muscular Strength, Physical Performance, and Musculoskeletal Symptoms in Hospitalized Patients With COVID-19.

Karasu Ayça Utkan AU Karataş Levent L Yıldız Yeşim Y Günendi Zafer Z

Archives of physical medicine and rehabilitation 20220911 1

<h4>Objective</h4>To investigate the course of muscle strength, musculoskeletal symptoms and physical performance over time in hospitalized COVID-19 patients, and their relation with disease severity at admission.<h4>Design</h4>Prospective cohort study.<h4>Setting</h4>Pandemic clinic of Gazi University Hospital, Ankara, Turkey.<h4>Participants</h4>76 adult COVID-19 patients (aged >18 years) were enrolled in the study between March 2021 and May 2021 (N=76). The participants were grouped as "mild, ...[more]

PMID: 36103903

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