One-Year Outcomes with Use of Anti-T-Lymphocyte Globulin in Patients Undergoing Kidney Transplantation: Results from a Prospective, Multicentric, Observational Study from India.

ABSTRACT:

Introduction

Large-scale Indian data on the use of anti-T-lymphocyte globulin (ATLG) (Grafalon^®) as induction therapy in kidney transplantation (KT) patients is lacking. The aim of this study was to determine the 1-year patient and graft survival outcomes with the use of ATLG as induction regimen in KT.

Methods

In a prospective, multicentric, observational study, adult patients who underwent ABO-compatible KT and had received ATLG as a part of induction were included in the study. The primary outcome measure was overall survival and death-censored graft survival at 12 months. The primary safety outcome was assessed by development of infectious complications and graft rejection.

Results

In total, 359 patients were included in this study. The mean age was 42.

SUBMITTER: Gang S 

PROVIDER: S-EPMC9464724 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature