Differential diagnosis and long-term outcomes of non-atrophic duodenal changes in children.

ABSTRACT:

Objectives and study

Gastrointestinal endoscopy is often performed when investigating abdominal complaints in children. While atrophic changes of the duodenal mucosa are usually caused by celiac disease, the prevalence and clinical significance of non-atrophic duodenal changes are less clear. We studied these issues in a large pediatric endoscopic cohort.

Methods

Comprehensive data on clinical features, diagnostic findings and long-term outcomes of children who had undergone upper gastrointestinal endoscopy with systematic duodenal sampling were collected. Study variables were compared between children with non-atrophic changes and normal histology, and between those with non-atrophic changes who did and did not receive a diagnosis.

Results

The study comprised 1,170 c

SUBMITTER: Kroger S 

PROVIDER: S-EPMC9464825 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature